Prioritizing recovery is essential to your ability to continually train at a high level as well to realize the benefits of training.*
Glutamine is an amino acid widely recognized for its role in protein synthesis and as one of the most popular supplements to take when looking to improve recovery from exercise.*
The problem is that supplementing with regular L-Glutamine is usually gobbled up in the GI tract, meaning very little is transported into the bloodstream and thereby, does next to nothing for recovery.*
However, research indicates that when L-Glutamine is combined with L-alanine, glutamine uptake is enhanced.*
Primeval Labs Glutamine supplies 1.25g each of L-Glutamine and L-Alanine to support protein synthesis and exercise recovery.*
Primeval Labs Glutamine is unflavored and can be mixed into your post-workout protein shake or taken with your serving of EAA Max.
- Glutamine is the most abundant and versatile amino acid in the body*
- In fact, 80% of the bodys glutamine content is found in skeletal muscle*
- Glutamine plays a role in gluconeogenesis and immune function*
- The versatile amino acid can also be used as a source of energy, a substrate for nucleotide synthesis, and a modulator of intermediary metabolism of amino acids*
- It also promotes water uptake as well as increase in sodium ion (Na+) uptake and the release of potassium ions (K+), which increase the cell volume and hydration*
- Strenuous exercise leads to a reduction in l-Glutamine
- Supplementation with free form L-Glutamine + L-alanine has been noted to increase plasma glutamine levels*
- Additional studies suggest that the combination of free form L-Glutamine + L-Alanine may improve the effects of resistance training in trained subjects*
- Beyond its role in protein synthesis, glutamine is also known to possess antioxidant and cytoprotective effects*
- L-Alanine is an non-essential amino acid that plays a role in carbohydrate metabolism, and immune function*
- It also provides energy for the brain, CNS, and skeletal muscle systems*
- Supplementation with free form L-alanine has been shown to spare L-glutamine metabolism in the gut and improve uptake by other tissues*[5,6]
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
- Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients. 2018;10(11):1564. Published 2018 Oct 23. doi:10.3390/nu10111564
- Petry, ƒ°. R., Cruzat, V. F., Heck, T. G., Leite, J. S. M., Homem de Bittencourt, P. I., & Tirapegui, J. (2014). Alanyl-glutamine and glutamine plus alanine supplements improve skeletal redox status in trained rats: Involvement of heat shock protein pathways. Life Sciences, 94(2), 130œ136. https://doi.org/https://doi.org/10.1016/j.lfs.2013.11.009
- Coqueiro, A. Y., Raizel, R., Hypƒ³lito, T. M., & Tirapegui, J. (2017). Effects of supplementation with L-glutamine and L-alanine in the body composition of rats submitted to resistance exercise. Revista Brasileira de Ciƒªncias Do Esporte, 39(4), 417œ423. https://doi.org/https://doi.org/10.1016/j.rbce.2017.06.003
- National Center for Biotechnology Information. PubChem Database. L-Alanine, CID=5950, https://pubchem.ncbi.nlm.nih.gov/compound/L-Alanine
- Cruzat VF, Pantaleao LC, Donato J, Jr, de Bittencourt PI, Jr, Tirapegui J. Oral supplementations with free and dipeptide forms of L-glutamine in endotoxemic mice: effects on muscle glutamine-glutathione axis and heat shock proteins. J Nutr Biochem. 2014;25:345œ352. doi: 10.1016/j.jnutbio.2013.11.009.
- Cruzat VF, Tirapegui J. Effects of oral supplementation with glutamine and alanyl-glutamine on glutamine, glutamate, and glutathione status in trained rats and subjected to long-duration exercise. Nutrition. 2009;25:428œ435. doi: 10.1016/j.nut.2008.09.014.